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svi genotipovi
all genotypes
Last Update: 2017-04-26
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liječeni genotipovi
on-therapy genotypes
Last Update: 2017-04-26
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genotipovi 2 ili 3:
genotype 2 or 3:
Last Update: 2017-04-26
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svi hcv genotipovi n = 197
all hcv genotypes n = 197
Last Update: 2017-04-26
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genotipovi 2 ili 3: preporučeno trajanje liječenja je 24 tjedna.
genotype 2 or 3: the recommended duration of treatment is 24 weeks.
Last Update: 2017-04-26
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najčešći hbv genotipovi bili su b (26%) i c (51%).
the most common hbv genotypes were b (26%) and c (51%).
Last Update: 2017-04-26
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Četvrto je ispitivanje provedeno na 201 bolesniku s virusom hepatitisa c (genotipovi 2 ili 3) koji nisu odgovorili na prethodno liječenje interferonom ili čija se infekcija ponovno pojavila.
the fourth study was done in 201 patients with hepatitis c virus (genotypes 2 or 3) who did not respond to previous treatment with interferon or whose infections came back.
Last Update: 2017-04-26
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određene mutacije gena gla mogu rezultirati stvaranjem abnormalno smotanih i nestabilnih mutiranih oblika enzima α-gal a. migalastat je farmakološki šaperon koji je osmišljen kako bi se selektivno i reverzibilno te s visokim afinitetom vezao za aktivna mjesta određenih mutiranih oblika enzima -gal a čiji genotipovi imaju mutacije koje omogućuju odgovor na liječenje.
certain gla mutations can result in the production of abnormally folded and unstable mutant forms of α-gal a. migalastat is a pharmacological chaperone that is designed to selectively and reversibly bind with high affinity to the active sites of certain mutant forms of -gal a, the genotypes of which are referred to as amenable mutations.
Last Update: 2017-04-26
Usage Frequency: 1
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