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plazmatické koncentrace metabolitu midazolamu, 1 '- hydroxymidazolamu, však byly opakovaným podáváním laropiprantu přibližně dvojnásobně zvýšeny.
cu toate acestea, concentraţia plasmatică a unui metabolit al midazolamului, 1 '- hidroximidazolam, a fost crescută de aproximativ 2 ori în cazul dozelor multiple de laropiprant.
Last Update: 2011-10-23
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1 '- hydroxymidazolam je metabolizován převážně uridindifosfátglukuronosyltransferázami (ugt) 2b4 a 2b7.
1 ’ - hidroximidazolamul este metabolizat predominant de către uridin difosfat glucuroniltransferazele (ugt) 2b4 şi 2b7.
Last Update: 2011-10-23
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