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gabapentins bindingssted er identificeret som alfa2 delta underenhed af de spændingsafhængige calciumkanaler.
the binding site for gabapentin has been identified as the alpha2-delta subunit of voltage-gated calcium channels.
gabapentins bindingssted er identificeret som alfa2 – delta underenhed af de spændingsafhængige calciumkanaler.
the binding site for gabapentin has been identified as the alpha2-delta subunit of voltage-gated calcium channels.
muligheden for lægemiddelinteraktioner ved p-gp’s bindingssted vil sandsynligvis afhænge af denne transportørs hæmningsgrad.
the potential for drug interactions at the p-gp site will likely depend on the degree of inhibition of this transporter.
entakapon bindes til humant albumin bindingssted ii, der også binder flere andre lægemidler, inklusiv diazepam og ibuprofen.
entacapone binds to human albumin binding site ii which also binds several other medicinal products, including diazepam and ibuprofen.
muligheden for interaktioner med lægemidler ved p-gp’s bindingssted vil sandsynligvis afhænge af denne transportørs hæmningsgrad.
the potential for drug interactions at the p-gp site will likely depend on the degree of inhibition of this transporter.
entakapon bindes til humant albumin - bindingssted ii, hvilket også kan binde adskillige andre lægemidler inklusive diazepam og ibuprofen.
4 entacapone binds to human albumin binding site ii which also binds several other medicinal products, including diazepam and ibuprofen.
muligheden for lægemiddelinteraktioner ved p-gp’s bindingssted vil sandsynligvis afhænge af, i hvor stor udstrækning denne transportør hæmmes.
the potential for drug interactions at the p-gp site will likely depend on the degree of inhibition of this transporter.
in-vitro data: entacapon bindes til humant albumin – bindingssted ii, der også binder flere andre lægemidler, inklusive diazepam og ibuprofen.
in vitro data: entacapone binds to human albumin binding site ii which also binds several other medicinal products, including diazepam and ibuprofen.
data fra dyreforsøg tyder på, at amlodipin binder til både dihydropyridin og ikke - dihydropyridin- bindingssteder.
experimental data suggest that amlodipine binds to both dihydropyridine and non-dihydropyridine binding sites.