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disse effekter formidles af endothelinbindinger til eta -og etb-receptorer i endothelium og vaskulære, glatte muskelceller.
these effects are mediated by endothelin binding to eta and etb receptors located in the endothelium b
Last Update: 2008-03-04
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neurohormonet endothelin-1 (et-1) er en af de mest potente vasokonstriktorer, der kendes, og kan også fremme fibrose, celleproliferation, hjertehypertrofi og remodellering og er pro-inflammatorisk.disse effekter formidles af endothelinbindinger til eta -og etb-receptorer i endothelium og vaskulære, glatte muskelceller.
resulting in increased cardiac output without increasing heart rate.the neurohormone endothelin-1 (et-1) is one of the most potent vasoconstrictors known and can also promote fibrosis, cell proliferation, cardiac hypertrophy, and remodeling and is pro-inflammatory.
Last Update: 2008-03-04
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