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dette kan skyldes byettas glukoseafhængige, insulinotropiske mekanisme (se pkt.
when exenatide was used in combination with metformin alone, no increase in the incidence of hypoglycaemia was observed over that of placebo in combination with metformin which may be due to this glucose-dependent insulinotropic mechanism.
Last Update: 2011-10-23
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ved at øge de endogene niveauer af disse inkretinhormoner øger vildagliptin betacellernes følsomhed over for glukose, og dermed forbedres den glukoseafhængige insulinsekretion.
by increasing the endogenous levels of these incretin hormones, vildagliptin enhances the sensitivity of beta cells to glucose, resulting in improved glucose-dependent insulin secretion.
Last Update: 2012-04-11
Usage Frequency: 3
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7 administration af vildagliptin resulterer i hurtig og fuldstændig hæmning af dpp- 4- aktiviteten, hvilket resulterer i øgede fastende og postprandiale endogene niveauer af inkretinhormonerne glp- 1 (glukagonlignende peptid 1) og gip (glukoseafhængigt insulinotropt polypeptid).
7 the administration of vildagliptin results in a rapid and complete inhibition of dpp-4 activity, resulting in increased fasting and postprandial endogenous levels of the incretin hormones glp-1 (glucagon-like peptide 1) and gip (glucose-dependent insulinotropic polypeptide).
Last Update: 2012-04-11
Usage Frequency: 5
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