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i et randomiseret, sammenlignende fase iii-studie, udført af gynaecological oncology group (gog 0179), blev topotecan + cisplatin (n = 147) sammenlignet med cisplatin alene (n = 146) for behandling af histologisk bekræftet, persisterende, recidiverende eller stadium ivb-cervixcancer, hvor kurativ intenderet behandling med kirurgi og/eller stråleterapi ikke var vurderet hensigtsmæssig.
in a randomised, comparative phase iii trial conducted by the gynaecological oncology group (gog 0179), topotecan plus cisplatin (n = 147) was compared with cisplatin alone (n = 146) for the treatment of histologically confirmed persistent, recurrent or stage ivb carcinoma of the cervix where curative treatment with surgery and/or radiation was not considered appropriate.
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