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gruppen af mtp-hæmmerne (microsomal triglyceride transfer protein inhibitors) har potentiale til at forstyrre udviklingen af
mtp inhibitors (microsomal trigylyceride transfer protein inhibitors) as a class, have the potential to disrupt yolk sac development and laboratory studies on rats and rabbits have shown evidence of embryolethality, teratogenicity, and developmental toxicity.
Last Update: 2008-03-04
Usage Frequency: 1
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dirlotapid er en potent selektiv hæmmer af microsomal-triglyceride-transfer-protein (mtp).
dirlotapide is a potent selective inhibitor of the microsomal triglyceride transfer protein (mtp).
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
gruppen af mtp (microsomal triglyceride transfer protein)-hæmmere har potentiale til at forstyrre udviklingen af blommesækken, og laboratorieundersøgelser i rotter og kaniner og har vist tegn på at de er embryoletale, teratogene og reproduktionstoksiske.
mtp (microsomal trigylyceride transfer protein) inhibitors as a class have the potential to disrupt yolk sac development and laboratory studies on rats and rabbits have shown evidence of embryolethality, teratogenicity, and developmental toxicity.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
aktive indholdsstoffer, som inhiberer aktiviteten af hepatiske, microsomale lægemiddelmetaboliserende enzymer fx ketoconazol, kan øge plasmakoncentrationen af de aktive indholdsstoffer i activelle.
active substances that inhibit the activity of hepatic microsomal drug metabolizing enzymes e.g. ketoconazole, may increase circulating levels of the active substances in activelle.
Last Update: 2012-04-12
Usage Frequency: 2
Quality: