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der blev ikke observeret nogen mål-organtoksicitet.
no target organ toxicity was observed.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
det var blevet argumenteret, at nyretumorerne var sekundære til vedvarende organtoksicitet.
it had been argued that the kidney tumours were secondary to sustained organ toxicity.
Last Update: 2014-02-06
Usage Frequency: 1
Quality:
i akutte dyreundersøgelser resulterede administration af meget høje doser lamivudin ikke i organtoksicitet.
administration of lamivudine at very high dose levels in acute animal studies did not result in any organ toxicity.
Last Update: 2017-04-26
Usage Frequency: 5
Quality:
da leflunomid er i kroppen i lang tid, kan det at skifte til et andet dmard (f. eks. methotrexate) uden at foretage "wash- out" - proceduren (se nedenfor) eventuelt føre til additiv risiko selv lang tid efter præparatskiftet (dvs. kinetiske interaktioner, organtoksicitet).
as leflunomide has a long persistence in the body, a switching to another dmard (e. g. methotrexate) without performing the washout procedure (see below) may raise the possibility of additive risks even for a long time after the switching (i. e. kinetic interaction, organ toxicity).
Last Update: 2012-04-11
Usage Frequency: 5
Quality:
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