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resistens medieres ved nedsat hæmmerbinding til den ændrede hbv-reverstranskriptase, og resistent hbv udviser nedsat replikationskapacitet i cellekulturer.
resistance is mediated by reduced inhibitor binding to the altered hbv reverse transcriptase, and resistant hbv exhibits reduced replication capacity in cell culture.
Last Update: 2017-04-26
Usage Frequency: 6
Quality:
for beskrivelse af andre nukleosidanalog-reverstranskriptase-inhibitorer (nrti) anvendt sammen med probenecid henvises til de relevante produktbeskrivelser.
for other nrti drugs administered concomitantly with probenecid, reference should be made to their respective prescribing information for any appropriate recommendations.
Last Update: 2017-04-26
Usage Frequency: 4
Quality: