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tem-celtest
tem cell testing
Last Update: 2017-04-06
Usage Frequency: 3
Quality:
in celtesten hadden lamivudine-resistente hbv-stammen, die ofwel de rtm204i-mutatie ofwel de rtl180m/rtm204v dubbel mutatie bevatten, een ≥1.000-voudig verminderde gevoeligheid voor telbivudine.
in cell-based assays, lamivudine-resistant hbv strains containing either the rtm204i mutation or the rtl180m/rtm204v double mutation had ≥ 1,000-fold reduced susceptibility to telbivudine.