Results for dfdctp translation from Dutch to English

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Dutch

de afname van de intracellulaire concentratie dctp potentieert aldus de incorporatie van dfdctp in dna.

English

thus, the reduced intracellular concentration of dctp potentiates the incorporation of dfdctp into dna.

Last Update: 2012-04-11
Usage Frequency: 2
Quality:

Dutch

als tweede gaat dfdctp de competitie aan met dctp voor de incorporatie in dna (zelfpotentiëring).

English

second, dfdctp competes with dctp for incorporation into dna (self-potentiation).

Last Update: 2012-04-11
Usage Frequency: 2
Quality:

Dutch

de cytotoxische activiteit van gemcitabine berust op het via twee werkingsmechanismen remmen van de dna-synthese door dfdcdp en dfdctp.

English

the cytotoxic effect of gemcitabine is due to inhibition of dna synthesis by two mechanisms of action by dfdcdp and dfdctp.

Last Update: 2012-04-11
Usage Frequency: 2
Quality:

Dutch

kinetiek van dfdctp deze metaboliet kan worden aangetroffen in mononucleaire cellen uit het perifere bloed; de onderstaande informatie verwijst naar deze cellen.

English

dfdctp kinetics this metabolite can be found in peripheral blood mononuclear cells and the information below refers to these cells.

Last Update: 2012-04-11
Usage Frequency: 2
Quality:

Dutch

bij plasmaconcentraties van gemcitabine hoger dan 5 µg/ml stijgen de dfdctp-spiegels niet, wat suggereert dat de vorming in deze cellen verzadigbaar is.

English

at gemcitabine plasma concentrations above 5 µg/ml, dfdctp levels do not increase, suggesting that the formation is saturable in these cells.

Last Update: 2012-04-11
Usage Frequency: 2
Quality:

Dutch

30 werkingsmechanisme cellulair metabolisme en werkingsmechanisme: gemcitabine (dfdc), dat een antimetaboliet van pyrimidine is, wordt door nucleosidekinase intracellulair omgezet in de actieve difosfaat(dfdcdp)- en trifosfaat(dfdctp)-nucleosiden.

English

gemcitabine (dfdc), which is a pyrimidine antimetabolite, is metabolised intracellularly by nucleoside kinase to the active diphosphate (dfdcdp) and triphosphate (dfdctp) nucleosides.

Last Update: 2012-04-11
Usage Frequency: 2
Quality:

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