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perindopril
perindopril
Last Update: 2011-10-23
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perindopril tert-butylaminezout
perindopril tert-butylamine salt
Last Update: 2011-10-23
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het gebruik van perindopril in
concomitant use of thiazide diuretics may increase the risk of lithium toxicity and enhance the already increased risk of lithium toxicity with ace inhibitors.
Last Update: 2011-10-23
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de plasmahalfwaardetijd van perindopril bedraagt 1 uur.
the plasma half-life of perindopril is equal to 1 hour.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
perindopril vermindert de hypertrofie van het linkerventrikel.
perindopril reduces peripheral vascular resistance, leading to blood pressure reduction.
Last Update: 2012-04-11
Usage Frequency: 2
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perindopril werkt via zijn actieve metaboliet, perindoprilaat.
perindopril acts through its active metabolite, perindoprilat.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
perindopril is gecontraïndiceerd tijdens het tweede en derde zwangerschapstrimester.
pregnancy and lactation (see section 4.3 “ contraindications” and section 4.6 “ pregnancy and lactation”).
Last Update: 2011-10-23
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perindopril kan uit de algemene circulatie verwijderd worden door hemodialyse.
perindopril may be removed from the general circulation by haemodialysis.
Last Update: 2012-04-11
Usage Frequency: 2
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perindopril verlaagt de perifere vaatweerstand, wat leidt tot een bloeddrukdaling.
hypertension perindopril is active in all grades of hypertension: mild, moderate, severe; a reduction in systolic and diastolic blood pressures in both supine and standing positions is observed.
Last Update: 2011-10-23
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het is onbekend of perindopril wordt uitgescheiden in de moedermelk bij de mens.
therefore the combination of perindopril with the above-mentioned drugs is not recommended (see section 4.4).
Last Update: 2012-04-11
Usage Frequency: 2
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2 mg perindopril tert-butylamine zout, overeenkomend met 1,669 mg perindopril
tablets 4 mg perindopril 2 mg
Last Update: 2011-10-23
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het gelijktijdig gebruik van deze middelen kan de hypotensieve effecten van perindopril versterken.
concomitant use of these agents may increase the hypotensive effects of perindopril.
Last Update: 2012-04-11
Usage Frequency: 2
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de huidige indicaties voor perindopril zijn de behandeling van hypertensie en van symptomatisch hartfalen.
perindopril is currently indicated for the treatment of hypertension and symptomatic heart failure”.
Last Update: 2012-04-11
Usage Frequency: 2
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na orale toediening, is de absorptie van perindopril snel en de piekconcentratie volledig in 1 uur.
after oral administration, the absorption of perindopril is rapid and the peak concentration complete within 1 hour.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
antihypertensiva en vasodilatatoren het gelijktijdig gebruik van deze middelen kan de hypotensieve effecten van perindopril versterken.
neutropenia/ agranulocytosis/ thrombocytopenia/ anaemia neutropenia/ agranulocytosis, thrombocytopenia and anaemia have been reported in patients receiving ace inhibitors.
Last Update: 2012-04-11
Usage Frequency: 2
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de aanvrager werd tevens verzocht om te verantwoorden dat het gunstige effect van perindopril zich niet beperkt tot een reductie van mi.
the applicant was also requested to justify the beneficial effect of perindopril beyond a mere reduction of mi.
Last Update: 2011-10-23
Usage Frequency: 1
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5.2 farmacokinetische gegevens na orale toediening, is de absorptie van perindopril snel en de piekconcentratie volledig in 1 uur.
5.2 pharmacokinetic properties after oral administration, the absorption of perindopril is rapid and the peak concentration complete within 1 hour.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
er werden stijgingen in de serumspiegel van kalium waargenomen bij sommige patiënten behandeld met ace-remmers, inclusief perindopril.
in these patients, treatment should be started under close medical supervision with low doses and careful dose titration.
Last Update: 2012-04-11
Usage Frequency: 2
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16 (0,3%) van de 6122 perindopril patiënten en 12 (0,2%) van de 6107 placebo patiënten.
16 (0.3%) of the 6122 perindopril patients and 12 (0.2%) of the 6107 placebo patients.
Last Update: 2011-10-23
Usage Frequency: 1
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2 mg perindopril tert-butylamine zout, overeenkomend met 1,669 mg perindopril voor hulpstoffen, zie rubriek 6.1.
2 mg perindopril tert-butylamine salt, equivalent to 1.669 mg perindopril
Last Update: 2011-10-23
Usage Frequency: 2
Quality:
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