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de c5-expressie in het panel van de in dit onderzoek onderzochte humane weefsels komt overeen met gepubliceerde rapporten over c5-expressie, aangezien de aanwezigheid van c5 is gemeld in glad en dwarsgestreept spierweefsel en in renaal proximaal tubulusepitheel.
c5 expression in the human tissue panel examined in this study is consistent with published reports of c5 expression, as c5 has been reported in smooth muscle, striated muscle, and renal proximal tubular epithelium.
Last Update: 2017-04-26
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bij jonge ratten die behandeld werden met valsartan (postnatale dagen 7 tot 70), veroorzaakten doses van slechts 1 mg/kg/dag aanhoudende onomkeerbare veranderingen van de nieren, bestaande uit tubulaire nefropathie (soms vergezeld van necrose van tubulusepitheel) en dilatatie van het nierbekken.
in juvenile rats treated with valsartan (postnatal days 7 to 70), doses as low as 1 mg/kg/day produced persistent irreversible kidney changes consisting of tubular nephropathy (sometimes accompanied by tubular epithelial necrosis) and pelvic dilatation.
Last Update: 2017-04-26
Usage Frequency: 1
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