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apixaban auc: ↑ 2-fold
apixaban auc: ↑ 2 gange
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
apixaban dabigatran etexilate rivaroxaban
apixaban dabigatran etexilat rivaroxaban
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
the active substance is apixaban.
aktivt stof: apixaban.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
apixaban n = 2,798 n(%/year)
apixaban n = 2.798 n(%/år)
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
apixaban has multiple routes of elimination.
apixaban har flere udskillelsesveje.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
apixaban can be taken with or without food.
apixaban kan tages sammen med eller uden føde.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
effect of apixaban on other medicinal products
apixabans virkning på andre lægemidler
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
apixaban is not a significant inhibitor of p-gp.
apixaban er ikke en signifikant hæmmer af p-gp.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
corresponding increases in clotting tests were observed for apixaban.
tilsvarende stigninger i koagulationstests blev set for apixaban.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
available data in animals have shown excretion of apixaban in milk.
tilgængelige data fra dyreforsøg har vist, at apixaban udskilles i mælk.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
intake with food does not affect apixaban auc or cmax at the 10 mg dose.
indtagelse af føde påvirker ikke apixabans auc eller cmax efter en dosis på 10 mg.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
it is unknown whether apixaban or its metabolites are excreted in human milk.
det vides ikke om apixaban eller dets metabolitter udskilles i modermælken.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
apixaban inhibits free and clot-bound factor xa, and prothrombinase activity.
apixaban hæmmer frit og fibrinbundet faktor xa samt protrombinaseaktivitet.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
at doses 25 mg apixaban displays dissolution limited absorption with decreased bioavailability.
ved doser på ≥ 25 mg apixaban ses en faldende biotilgængelighed forårsaget af opløsningsbegrænset absorption.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
effects of coagulation markers when switching from rivaroxaban, dabigatran, or apixaban to edoxaban
virkningen af koagulationsmarkører, når der skiftes fra rivaroxaban, dabigatran eller apixaban til edoxaban
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
administration of activated charcoal reduces apixaban exposure (see section 4.9).
administration af aktivt kul nedsætter apixaban-eksponering (se pkt.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
no clinically significant pharmacokinetic or pharmacodynamic interactions were observed when apixaban was coadministered with atenolol or famotidine.
der blev ikke observeret klinisk signifikante farmakokinetiske eller farmakodynamiske interaktioner, når apixaban blev givet samtidigt med atenolol eller famotidin.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
apixaban has no direct effects on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin.
apixaban har ingen direkte effekt på trombocytaggregationen, men hæmmer indirekte trombocytaggregationen induceret af trombin.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
apixaban is a potent, oral, reversible, direct and highly selective active site inhibitor of factor xa.
apixaban er en potent, oral, reversibel, direkte og yderst selektiv faktor xa-hæmmer.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
the overall incidence of adverse reactions related to bleeding with apixaban was 10% in the apixaban vs enoxaparin studies.
den samlede bivirkningsfrekvens relateret til blødning pga. apixaban var 10% i apixaban- versus enoxaparinstudierne.
Last Update: 2017-04-26
Usage Frequency: 1
Quality: