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the accumulation of bosentan in hepatocytes leading to cytolysis with potentially severe damage of the liver, or an immunological mechanism, are not excluded.
akkumuleringen af bosentan i hepatocytter, som kan føre til cytolyse med potentiel alvorlig leverskade eller en immunologisk mekanisme, kan ikke udelukkes.
Last Update: 2017-04-26
Usage Frequency: 5
Quality:
alemtuzumab acts through antibody-dependent cellular cytolysis and complement-mediated lysis following cell surface binding to t and b lymphocytes.
alemtuzumab virker via antistofafhængig cellulær cytolyse og komplementmedieret lyse efterfølgende celleoverfladebinding til t- og b-lymfocytter.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
the clinical presentation may include fever, fatigue, myalgia, headache, hypotension, progressing to one or more of metabolic acidosis, muscle and liver cytolysis, lymphocytopenia and thrombocytopenia, renal failure and respiratory failure.
det kliniske billede kan inkludere feber, træthed, myalgi, hovedpine, hypotension, der udvikler sig til en eller flere af følgende tilstande: metabolisk acidose, muskel - og levercytolyse, lymfocytopeni og thrombocytopeni, nyresvigt og respiratorisk svigt.
Last Update: 2012-04-12
Usage Frequency: 4
Quality: