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in post marketing experience, a differentiation syndrome, like retinoic acid syndrome, has also been reported for the treatment of malignancies other than apl with trisenox.
turuletulekujärgselt on teatatud diferentseerumissündroomist (nt retinoehappesündroomist) trisenox’i kasutamisel ka muude pahaloomuliste kasvajate raviks peale apl.
based on the plasma concentrations observed in patients, milk concentrations of 9-cis-retinoic acid probably pose a low risk for the infant.
patsientidel täheldatud plasmakontsentratsioonide põhjal võib öelda, et ilmselt on piima 9-cis-retinoolhappe kontsentratsioonid lapsele väheohtlikud.
the range and frequency of detection of quantifiable plasma 9-cis-retinoic acid concentrations in patients with ks applying the medicinal product to up to 64 lesions were comparable to respective values in untreated patients.
9-cis-retinoolhappe mõõdetava plasma kontsentratsiooni tase ja sagedus ks-iga patsientidel, kes manustasid ravimit kuni 64-le lesioonile, olid võrreldavad vastavate väärtustega patsientidel, kes ei saanud ravi.
the results suggest that alitretinoin absorbs light in the uv range and is subject to photodegradation to other isomers (predominantly all-trans-retinoic acid).
tulemused näitasid, et alitretinoiin neelab valgust uv lainepikkusel ja muutub fotodegradatsioonil teisteks isomeerideks (peamiselt all-trans-retinoolhape).
whereas, with a view to the protection of public health, it is necessary to prohibit the use of 3,4,5-tribromosalicylanilide, phytolacca spp. and their preparations, retinoic acid and certain hair-dyeing substances;
seoses rahva tervise kaitsega tuleb keelata 3,4,5-tribromosalitsüülaniliidi, phytolacca spp. ja nende valmististe, retinoiinhappe ja teatavate juuksevärvide kasutamine;