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cftr
transmembraaninen konduktanssinsäätäjä kystisessä fibroosissa
Last Update: 2014-12-09
Usage Frequency: 3
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cftr mice
sisäsiittoiset cftr-hiiret
Last Update: 2014-12-09
Usage Frequency: 1
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mice, cftr
sisäsiittoiset cftr-hiiret
Last Update: 2014-12-09
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cftr protein
transmembraaninen konduktanssinsäätäjä kystisessä fibroosissa
Last Update: 2014-12-09
Usage Frequency: 3
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mouse, cftr
sisäsiittoiset cftr-hiiret
Last Update: 2014-12-09
Usage Frequency: 1
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inbred cftr mice
sisäsiittoiset cftr-hiiret
Last Update: 2014-12-09
Usage Frequency: 1
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cftr mice, inbred
sisäsiittoiset cftr-hiiret
Last Update: 2014-12-09
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inbred cftr mouse
sisäsiittoiset cftr-hiiret
Last Update: 2014-12-09
Usage Frequency: 1
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cftr mouse, inbred
sisäsiittoiset cftr-hiiret
Last Update: 2014-12-09
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cftr (cystic fibrosis transmembrane conductance regulator)
transmembraaninen konduktanssinsäätäjä kystisessä fibroosissa
Last Update: 2014-12-09
Usage Frequency: 1
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cystic fibrosis is caused by mutations in the cftr gene.
kystinen fibroosi johtuu cftr-geenin mutaatiosta.
Last Update: 2017-04-26
Usage Frequency: 1
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cystic fibrosis transmembrane conductance regulator (cftr) protein
transmembraaninen konduktanssinsäätäjä kystisessä fibroosissa
Last Update: 2014-12-09
Usage Frequency: 1
Quality:
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trial in patients with cf who are heterozygous for the f508del mutation in the cftr gene
tutkimus kystistä fibroosia sairastavilla potilailla, jotka olivat heterotsygoottisia cftr-geenin f508del-mutaation suhteen
Last Update: 2017-04-26
Usage Frequency: 1
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study 3: study in patients with cf with the f508del mutation in the cftr gene
tutkimus 3: tutkimus kystistä fibroosia sairastaville potilaille, joiden cftr-geenissä on f508del- mutaatio
Last Update: 2017-04-26
Usage Frequency: 1
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ivacaftor helps certain abnormal cftr proteins open more often to improve chloride movement in and out of the cell.
ivakaftori auttaa tiettyjä poikkeavia cftr-proteiineja avautumaan useammin, jotta kloridin liikkuminen solujen sisään ja soluista ulos helpottuu.
Last Update: 2017-04-26
Usage Frequency: 1
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it should be prescribed only to patients aged 12 years and above confirmed to have the f508del mutation in both copies of the cftr gene.
sitä saa määrätä vain yli 12-vuotiaille potilaille, joilla on vahvistetusti f508del-mutaatio kummassakin cftr-geenin kopiossa.
Last Update: 2017-04-26
Usage Frequency: 1
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orkambi contains two active substances, lumacaftor and ivacaftor that work together to improve the function of the abnormal cftr protein.
orkambi sisältää kahta vaikuttavaa ainetta, lumakaftoria ja ivakaftoria, jotka yhdessä parantavat poikkeavan cftr proteiinin toimintaa.
Last Update: 2017-04-26
Usage Frequency: 1
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cells contain two copies of the cftr gene; orkambi is used in patients in whom both copies are affected by the f508del mutation.
soluissa on kaksi cftr-geenin kopiota; orkambia käytetään potilaille, joiden kummassakin kopiossa on f508del-mutaatio.
Last Update: 2017-04-26
Usage Frequency: 1
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ivacaftor is a potentiator of the cftr protein, i.e., in vitro ivacaftor increases cftr channel gating to enhance chloride transport.
ivakaftori on cftr-proteiinin tehostaja, toisin sanoen ivakaftori lisää in vitro kloridin kuljetusta
Last Update: 2017-04-26
Usage Frequency: 1
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clinical efficacy in patients with the g970r mutation of the cftr gene could not be established (see section 5.1).
kliinistä tehoa potilailla, joilla oli cftr- geenin g970r-mutaatio, ei voitu varmistaa (ks. kohta 5.1).
Last Update: 2017-04-26
Usage Frequency: 1
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