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the direct effects of acrolein on the immune system (including host resistance, pulmonary bacterial clearance, antibody responsiveness, lymphocyte blastogenesis and respiratory damage) have been investigated in in vivo studies conducted with rats (bouley et al., 1976; sherwood et al., 1986; leach et al., 1987) and mice (jakab, 1977; astry and jakab, 1983; aranyi et al., 1986) exposed via inhalation.
les effets directs de l'acroléine sur le système immunitaire (y compris la résistance de l'hôte, la clairance bactérienne pulmonaire, la réactivité des anticorps, la blastogenèse des lymphocytes et les dommages respiratoires) ont été examinés dans le cadre d'études in vivo portant sur des rats (bouley et al., 1976; sherwood et al., 1986; leach et al., 1987) et sur des souris (jakab, 1977; astry et jakab, 1983; aranyi et al., 1986) exposés par inhalation.
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