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by inhibiting the normal catabolism of tyrosine in patients with ht-1, nitisinone prevents the accumulation of the toxic intermediates maleylacetoacetate and fumarylacetoacetate.
durch die hemmung des normalen tyrosinabbaustoffwechsels bei patienten mit ht-1 verhindert nitisinon die ansammlung der toxischen zwischenprodukte maleylacetoacetat und fumarylacetoacetat.
Last Update: 2017-04-26
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