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nfkb
transkriptionsfaktor nf-kb
Last Update: 2014-12-09
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substituted indoles for modulating nfkb activity
substituierte indole zur modulierung von nfkb-aktivitÄt
Last Update: 2014-11-28
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upon overexpression, dr4 and dr5 can also induce activation of nfkb (chaudhary et al., 1997; schneider et al., 1997; sheridan et al., 1997). because ligand activation of this response requires 100-1000-fold higher concentrations of apo2l/trail than of tnf (ashkenazi et al., 1999), the physiological significance of nfkb activation by dr4 and dr5 remains uncertain.
nach Überexpression, dr4 und dr5 auch induzieren die aktivierung von nfkb (chaudhary et al, 1997;. schneider et al, 1997;.. sheridan et al, 1997). da ligand aktivierung dieser reaktion erfordert 100-1000-fach höhere konzentrationen als apo2l/trail von tnf (ashkenazi et al., 1999), die physiologische bedeutung des nfkb-aktivierung durch dr4 und dr5 bleibt ungewiss.
Last Update: 2011-03-14
Usage Frequency: 2
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