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English

tacrolimus is also considerably metabolised in the intestinal wall.

Icelandic

takrólímus umbrotnar einnig talsvert í þarmavegg.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

the good news is that education levels in europe have risen considerably.

Icelandic

góðu fréttirnar eru að menntunarstigið í evrópu hefur hækkað umtalsvert.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

depending on the different pt reagents used, the slope differed considerably.

Icelandic

hallinn er töluvert mismunandi og fer eftir prófefni pt.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

these levels are considerably higher than levels achieved with therapeutic doses.

Icelandic

Þessi gildi eru umtalsvert hærri en þau gildi sem nást með meðferðar- skömmtum.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

ritonavir inhibits cyp3a, thereby increasing the plasma concentrations of darunavir considerably.

Icelandic

ritonavir hamlar cyp3a og eykur þannig umtalsvert plasmaþéttni darunavirs.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

increase the risk of bleeding complications considerably enhance the effect of refludan on aptt prolongation.

Icelandic

aukið hættu á blæðingarvandamálum aukið áhrif refludan á aptt umtalsvert.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

cobicistat and ritonavir inhibit cyp3a, thereby increasing the plasma concentrations of darunavir considerably.

Icelandic

cobicistat og ritonavir hamla cyp3a og eykur þannig umtalsvert plasmaþéttni darunavirs.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

clearance of ceplene is almost twice as high in females resulting in considerably lower systemic exposure than in males.

Icelandic

Úthreinsun ceplene er næstum því tvisvar sinnum meiri hjá konum sem leiðir af sér talsvert minni almenna útsetningu en hjá körlum.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

at doses that were considerably higher than the pharmacologically effective doses, ibandronic acid did not have any effect on bone mineralisation.

Icelandic

við skammta sem voru töluvert stærri en lyfjafræðilega virkir skammtar hafði íbandrónsýra engin áhrif á steinefnaútfellingu í beinum.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

if clinical response to treatment is considerably shorter than expected, a re-evaluation of the diagnosis is necessary.

Icelandic

ef verkun lyfsins varir til muna skemur en gert hafði verið ráð fyrir, skal endurmeta sjúkdómsgreiningu.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

there are, however, encouraging signs that growth inrenewable energy can be considerably accelerated with theright mix of support measures.

Icelandic

hins vegar eru blikur á lofti sem benda til að vöxtur íendurnýjanlega orkugeiranum geti orðið þó nokkuð hraðarimeð réttri blöndu stuðningsaðgerða.

Last Update: 2014-02-06
Usage Frequency: 1
Quality:

English

average s­content of fuels dropped considerably (40%) over 2 years and consequently significant s emission reductions were achieved.

Icelandic

innihald brennisteins í eldsneyti lækkaði aò meòaltali verulega (40%) á tveimur árum og í kjöífario náòist umtalsverð lækkun á brennisteini í útblæstri.

Last Update: 2014-02-06
Usage Frequency: 1
Quality:

English

as transport is expected to increase considerably, transport-related emissions are also expected to rise, intensifying air pollution in cities.

Icelandic

vegna þess art búist er við veralegri aukningu á flutningum er þess einnig vænst aö útstreymi frá flutningum aukist og þá eykst loftmengun í borgum.

Last Update: 2014-02-06
Usage Frequency: 1
Quality:

English

after oral administration, oteracil was distributed at high concentrations in normal gastrointestinal tract tissues while considerably lower concentrations were seen in blood and tumour tissue in animal studies.

Icelandic

Í kjölfar inntöku dreifðist óterasíl af miklum styrk í eðlilegan vef í meltingarvegi en í mun minni styrk í blóði og æxlisvef í dýrarannsóknum.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

animal reproduction studies with formoterol have shown a somewhat reduced fertility in male rats at high systemic exposure and implantation losses as well as decreased early postnatal survival and birth weight at considerably higher systemic exposures than those reached during clinical use.

Icelandic

rannsóknir með formóteróli á æxlun dýra hafa sýnt að frjósemi hjá karlkyns rottum minnkar við mikla altæka útsetningu og fanglát eftir hreiðrun og minni lífslíkur nýfæddra dýra og minni fæðingarþyngd sáust við umtalsvert hærri altæka útsetningu en næst við klíníska notkun.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

aromatic and aliphatic hydroxylation or glucuronidation metabolites are present in very low levels, display considerably lower anti-hiv activity and do not contribute to the overall antiviral activity of elvitegravir.

Icelandic

arómatísk og alifatísk hýdroxýlering eða glúkúroníðun umbrotsefna koma fram í mjög litlum mæli, þau sýna mun minni virkni gegn hiv og gegna engu hlutverki við heildarvirkni elvitegravírs gegn veirum.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

plasma histamine concentrations were highly variable and were considerably higher in the groups of patients with moderate or severe hepatic impairment (medians 10 and 5 times the normal volunteers respectively).

Icelandic

Þéttni histamíns í plasma var mjög breytileg og töluvert hærri í þeim hópum sjúklinga sem voru með miðlungs eða alvarlega skerðingu á lifrarstarfsemi (miðgildi annars vegar 10 og hins vegar 5 sinnum hærra, en hjá heilbrigðum sjálfboðaliðum).

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

these data support extrapolation of this finding to all antacids because the reduction in exposure when cellcept was co- administered with magnesium and aluminium hydroxides is considerably less than when cellcept was co-administered with ppis.

Icelandic

Þessar niðurstöður styðja að það sama eigi við um öll sýrubindandi lyf, þar sem minnkun á útsetningu þegar cellcept er gefið samtímis magnesíum hýdroxíði og álhýdroxíði er verulega minni en þegar cellcept er gefið samtímis prótónpumpuhemlum.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

given that the heart rate may fluctuate considerably over time, serial heart rate measurements, ecg or ambulatory 24-hour monitoring should be considered when determining resting heart rate before initiation of ivabradine treatment and in patients on treatment with ivabradine when titration is considered.

Icelandic

Þar sem hjartsláttartíðni getur verið mjög breytileg með tímanum á að íhuga endurteknar mælingar á hjartsláttartíðni, með hjartarafriti eða með sólarhrings hjartalínuriti, þegar hjartsláttartíðni í hvíld er ákvörðuð áður en meðferð með ivabradini er hafin og þegar íhugað er að breyta skömmtum hjá sjúklingum sem fá ivabradin.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

a loading dose should be considered in addition to a new maintenance dose when it is necessary to considerably increase sirolimus trough concentrations: rapamune loading dose = 3 x (new maintenance dose – current maintenance dose).

Icelandic

Íhuga skal hleðsluskammt til viðbótar við nýjan viðhaldsskammt, þegar nauðsynlegt er að auka verulega lágstyrk sirolimus: rapamune hleðsluskammtur = 3 x (nýr viðhaldsskammtur – núverandi viðhaldsskammtur).

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

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