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microsome
microsomi
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human liver microsome studies identified cyp1a2 and cyp2c8 as the enzymes responsible for eltrombopag oxidation.
studi nel microsoma epatico umano hanno identificato cyp1a2 e cyp2c8 come gli enzimi responsabili della ossidazione di eltrombopag.
and yamasaki e., (1975) methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test.
(1975), methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test, mutation res., 31, pp.
in vitro studies using human liver microsomes and cdna-expressed p450 enzymes have shown limited cyp 3a4-mediated metabolism.
gli studi in vitro su microsomi di fegato umano ed enzimi p450 espressi dal cdna hanno dimostrato che il metabolismo mediato dal cyp 3a4 era limitato.