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English

her2-overexpressing population

Latvian

populācija ar pārmērīgu her2 ekspresiju

Last Update: 2017-04-26
Usage Frequency: 1
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English

erbb2 overexpressing tumours are defined by ihc3+, or ihc2+ and gene amplification or gene amplification alone.

Latvian

audzēji ar erbb2 pārmērīgu ekspresiju tiek noteikti ar ihc3+ vai ihc2+ un gēnu amplifikāciju vai tikai ar gēnu amplifikāciju.

Last Update: 2012-04-10
Usage Frequency: 2
Quality:

English

tigecycline is a substrate of p-gp based on an in vitro study using a cell line overexpressing p-gp.

Latvian

tigeciklīns ir p-gp substrāts, pamatojoties uz pētījumu in vitro, izmantojot šūnu līnijas p-gp ekspresiju.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

in vitro, trastuzumab-mediated adcc has been shown to be preferentially exerted on her2 overexpressing cancer cells compared with cancer cells that do not overexpress her2.

Latvian

in vitro pierādīts, ka trastuzumaba mediēta aaŠc veiksmīgāk izpaužas pret vēža šūnām ar pārmērīgu her2 ekspresiju, salīdzinot ar vēža šūnām, kam nav pārmērīgas her2 ekspresijas.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

her2 (erbb2) overexpressing tumours are defined by ihc3+, or ihc2+ with gene amplification or gene amplification alone.

Latvian

audzēji ar pārmērīgu her2 (erbb2) ekspresiju tiek noteikti ar ihc3+ vai ihc2+ un gēnu amplifikāciju vai tikai ar gēnu amplifikāciju.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

eligible patients were women with stage iv erbb2 gene amplified (or protein overexpressing) metastatic breast cancer who had been exposed to treatment with anthracyclines and taxanes.

Latvian

dalībai pētījumā piemērotas pacientes bija sievietes ar iv stadijas metastātisku krūts vēzi, kurām bija erbb2 gēna amplifikācija (vai pārmērīga atbilstošā proteīna ekspresija) un kas bija saņēmušas terapiju ar antraciklīniem un taksāniem.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

in the her2-overexpressing population, only 2 patients were enrolled who had received prior trastuzumab, 2 patients had received prior aromatase inhibitor therapy, and approximately half had received tamoxifen.

Latvian

to pacienšu grupā, kurām bija vērojama pārmērīga her2 ekspresija, tika iesaistītas tikai 2 pacientes, kuras iepriekš bija saņēmušas trastuzumabu; 2 pacientes iepriekš bija saņēmušas aromatāzes inhibitoru terapiju un aptuveni puse pacienšu bija saņēmušas tamoksifēnu.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

English

a randomised phase iii study (egf111438) (n=540) compared the effect of the two regimens on the incidence of cns as site of first relapse in women with her2 overexpressing metastatic breast cancer.

Latvian

randomizētā iii fāzes pētījumā (egf111438) (n=540) tika salīdzināta abu shēmu ietekme uz cns kā pirmā recidīva lokalizācijas sastopamību sievietēm ar metastātisku krūts vēzi, kurām bija pārmērīga her2 ekspresija.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

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