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bh4 is a cofactor for nitric oxide synthetase.
bh4 ir slāpekļa oksīda sintetāzes kofaktors.
Last Update: 2017-04-26
Usage Frequency: 2
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carglumic acid has been shown in vitro to activate liver carbamoyl phosphate synthetase.
in vitro karglumīnskābe aktivē aknu karbamilfosfāta sintetāzi.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
once in the cell, pemetrexed is rapidly and efficiently converted to polyglutamate forms by the enzyme folylpolyglutamate synthetase.
Šūnā enzīma folipoliglutamāta sintetāzes ietekmē pemetrekseds tiek ātri un efektīvi pārvērsts par poliglutamāta formām.
Last Update: 2017-04-26
Usage Frequency: 3
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ammonaps is indicated as adjunctive therapy in the chronic management of urea cycle disorders, involving deficiencies of carbamylphosphate synthetase, ornithine transcarbamylase or argininosuccinate synthetase.
ammonaps izmanto kā papildu medikamentu hronisku urīnvielas cikla traucējumu ārstēšanā, kas ietver karbamila fosfāta sintetāzes, ornitīna transkarbamilāzes vai arginīna sukcināta sintetāzes deficīta gadījumus.
Last Update: 2017-04-26
Usage Frequency: 3
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carglumic acid was shown to decrease blood ammonia levels and increase urea levels in blood and urine, whereas the liver content of carbamoyl phosphate synthetase activators was significantly increased.
izrādījās, ka karglumīnskābe samazināja amonjaka līmeni asinīs un paaugstināja urīnvielas līmeni asinīs un urīnā, turpretim karbamilfosfāta sintetāzes aktivētāju daudzums aknās ievērojami paaugstinājās.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
carglumic acid is a structural analogue of n-acetylglutamate, which is the naturally occurring activator of carbamoyl phosphate synthetase, the first enzyme of the urea cycle.
karbamilfosfāta sintetāze ir urīnvielas cikla pirmais ferments.
Last Update: 2011-10-23
Usage Frequency: 1
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after a single dose, intracellular and serum activity of 2-5a synthetase and serum concentrations of beta-2 microglobulin and neopterin increase within 24 hours, and start to decline within 2 days.
pēc vienreizējas devas 24 stundu laikā palielinās intracelulārā un seruma 2- 5a sintetāzes aktivitāte un beta- 2 mikroglobulīna un neopterīna koncentrācija serumā, kas sāk pazemināties pēc 2 dienām.
Last Update: 2012-04-10
Usage Frequency: 2
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pegintron pegintron pharmacodynamics were assessed in a rising single-dose trial in healthy subjects by examining changes in oral temperature, concentrations of effector proteins such as serum neopterin and 2’5’- oligoadenylate synthetase (2’5’-oas), as well as white cell and neutrophil counts.
15 pegintron pegintron farmakodinamiku pētīja pieaugošas vienreizējas devas pētījumā ar veseliem cilvēkiem, vērtējot temperatūras pārmaiņas mutē, efektoro olbaltumvielu, piemēram, seruma neopterīna un 2’ 5 ’ – oligoadenilāta sintetāzes (2’ 5 ’ – oas), koncentrācijas pārmaiņas, kā arī leikocītu un neitrofīlo leikocītu skaita pārmaiņas.
Last Update: 2012-04-10
Usage Frequency: 11
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