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atorvastatin is eliminated primarily in bile following hepatic and/ or extrahepatic metabolism.
ne visos pakuotės gali būti tiekiamos rinkai
Last Update: 2011-10-23
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in the rat carcinogenicity study, benign tumours were found in the small bowel and the extrahepatic bile ducts.
kancerogeninio poveikio tyrimo su žiurkėmis metu plonojoje žarnoje ir ekstrahepatiniuose tulžies latakuose rasta gerybinių navikų.
Last Update: 2017-04-26
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extrahepatic metabolism by cyp3a4 in intestine, cyp1a1 in lung, and 1b1 in tumour tissue potentially contribute to the metabolic clearance of erlotinib.
erlotinibo metabolinis klirensas gali priklausyti ir nuo jo metabolizmo ne kepenyse: nuo cyp3a4 – žarnyne, nuo cyp1a1 – plaučiuose ir nuo 1b1 – navikiniame audinyje.
Last Update: 2017-04-26
Usage Frequency: 5
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the total clearance of iloprost is about 20 ml/kg/min, which indicates extrahepatic contribution to the metabolism of iloprost.
bendras iloprosto klirensas yra apie 20 ml/kg/min., kas rodo ir ekstrahepatinį iloprosto metabolizmą.
Last Update: 2017-04-26
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atorvastatin is eliminated primarily in bile following hepatic and/or extrahepatic metabolism.however, the medicinal product does not appear to undergo significant enterohepatic recirculation.
kepenyse ir (arba) ne kepenyse metabolizuotas atorvastatinas eliminuojamas daugiausiai su tulzimi, taciau kepen ir zarnyno kraujotakos rat daug jo nepatenka.
Last Update: 2008-03-04
Usage Frequency: 4
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this should be considered in conjunction with other factors, such as hcv genotype, age, extrahepatic manifestations, risk of transmission, etc. which influence the decision to treat or not.
dl to, kai sprendziama ar gydyti siuo vaistu, btina tai atsizvelgti, kaip ir kitus kriterijus, pvz., hcv genotip, paciento amzi, ne kepen simptom buvim, uzkrato pernesimo rizik ir t. t.
Last Update: 2008-03-04
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in the prespecified stratification factors (ecog status, presence or absence of macroscopic vascular invasion and/or extrahepatic tumour spread) the hazard ratio consistently favoured nexavar over placebo.
is anksto nustatytuose stratifikacijos veiksniuose (ecog stadija, makroskopins kraujagysli invazijos ir (arba) ekstrahepatinio naviko paplitimo buvimas ar nebuvimas) nexavar rizikos santykis buvo nuolat palankesnis nei placebo.
Last Update: 2008-03-04
Usage Frequency: 1
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