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endothelin antagonist
antagonisti tal-endotelin
Last Update: 2017-04-26
Usage Frequency: 1
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endothelin receptor antagonist
orveljanza mill-viċin ta’ effetti
Last Update: 2017-04-26
Usage Frequency: 1
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alternative endothelin receptor antagonists may be considered.
antagonisti alternattivi tar-riċetturi ta’ endothelin jistgħu jiġu kkunsidrati.
Last Update: 2017-04-26
Usage Frequency: 1
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endothelin plays a significant role in the pathophysiology of pah.
l- endotelina għandha rwol importanti fil- patofisjoloġija ta 'pah.
Last Update: 2011-10-23
Usage Frequency: 1
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endothelin-1 receptor antagonists (e.g. bosentan)
antagonisti tar-riċettur endothelin-1 (eż. bosentan)
Last Update: 2017-04-26
Usage Frequency: 1
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tracleer tablets belong to the class of medicines called endothelin receptor antagonists.
il- pilloli tracleer jagħmlu parti mill- klassi ta ’ mediċini msejħa antagonisti tar- riċetturi ta ’ endothelin.
Last Update: 2012-04-10
Usage Frequency: 2
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these effects are mediated by endothelin binding to eta and etb receptors located in the endothelium b
dawn l- effetti jseħħu billi endothelin jeħel mar- riċetturi eta u etb li qegħdin fl- endotilju u fiċ- ċelluli tal- muskoli l- lixxi vaskulari.
Last Update: 2012-04-10
Usage Frequency: 2
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endothelin receptor antagonists, as a class, have been associated with liver function abnormalities.
bħala kategorija, antagonisti tar-riċettur endothelin, ġew assoċjati ma’ anormalitajiet tal-funzjoni tal-fwied.
Last Update: 2017-04-26
Usage Frequency: 3
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the mechanism of liver toxicity is not fully documented and it might vary between endothelin receptor antagonists.
il-mekkaniżmu ta’ tossiċita’ tal-fwied mhix dokumentata kompletament u tista’ tvarja bejn antagonisti tar-riċettur endothelin.
Last Update: 2017-04-26
Usage Frequency: 1
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the active substance in opsumit, macitentan, works by blocking ‘endothelin receptors’.
is-sustanza attiva f’opsumit, il-macitentan, taħdem billi timblokka r-‘riċetturi ta’ endothelin’.
Last Update: 2017-04-26
Usage Frequency: 1
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the safety and efficacy of combinations of tadalafil and other endothelin-1 receptor antagonists have not been studied.
l-effikaċja u s-sigurtà ta’ meta tadalafil u l-antagonisti l-oħra ta’ emdothelin-1 jittieħdu flimkien ma ġewx studjati.
Last Update: 2017-04-26
Usage Frequency: 1
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development of testicular tubular atrophy and impaired fertility has been linked with chronic administration of endothelin receptor antagonists in rodents.
Żvilupp ta’ atrofija tubulari tat-testikoli u fertilità imdgħajfa ġew marbuta ma’ għoti kroniku ta’ antagonisti tar-riċettur ta’ endothelin f’annimali gerriema.
Last Update: 2017-04-26
Usage Frequency: 1
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the binding affinity of 4-hydroxymethyl ambrisentan for the human endothelin receptor is 65-fold less than ambrisentan.
l- affinita 'tal- irbit ta' 4- hydroxymethyl ambrisentan għar- riċettur ta 'l- endotelina fil- bniedem hi 65 darba inqas minn ambrisentan.
Last Update: 2011-10-23
Usage Frequency: 1
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the active substance in volibris, ambrisentan, blocks the receptors for a hormone called endothelin, which causes blood vessels to constrict.
is- sustanza attiva f' volibris, ambrisentan, timblokka r- riċetturi għal ormon imsejjaħ endothelin, li jikkawża t- tidjieq tal- vażi tad- demm.
Last Update: 2011-10-23
Usage Frequency: 1
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the use of prostacyclin, prostacyclin analogues and endothelin receptor antagonists was not permitted as add-on therapy, and neither was arginine supplementation.
l-użu ta’ prostacyclin, prostacyclin analogues u endothelin receptor antagonists ma kienx permess bħala terapija miżjuda, u lanqas suppliment ta’ arginine.
Last Update: 2017-04-26
Usage Frequency: 3
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elevations of liver aminotransferases (ast, alt) have been associated with pah and with endothelin receptor antagonists (eras).
elevazzjonijiet ta’ aminotransferases tal-fwied (ast, alt) kienu assoċjati ma’ pah u ma’ antagonisti tar-riċettur ta’ endothelin (eras – endothelin receptor antagonists).
Last Update: 2017-04-26
Usage Frequency: 1
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by blocking the effect of endothelin, volibris allows the vessels to dilate (expand), helping to lower the blood pressure and improving symptoms.
billi jimblokka l- effett ta 'endothelin, volibris iħalli l- vażi jinfetħu (jespandu), u jgħin biex ibaxxi l- pressjoni tad- demm u jtejjeb is- sintomi.
Last Update: 2011-10-23
Usage Frequency: 1
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in pulmonary arterial hypertension and heart failure, in the absence of endothelin receptor antagonism, elevated et- 1 concentrations are strongly correlated with the severity and prognosis of these diseases.
fil-każ ta’ pressjoni għolja arterjali pulmonari u kollass tal- qalb, u fl-assenza ta’ l-antagoniżmu tar-riċettur ta’ endothelin, konċentrazzjonijiet għolja ta’ et-1 huma kkorrelati mas-severità u mal-pronjosi ta’ dan il-mard.
Last Update: 2017-04-26
Usage Frequency: 4
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the neurohormone endothelin-1 (et-1) is one of the most potent vasoconstrictors known and can also promote fibrosis, cell proliferation, cardiac hypertrophy, and remodeling and is pro-inflammatory.
32 in- newro- ormon endothelin- 1 (et- 1) huwa wieħed mis- sustanzi magħrufa l- iktar qawwija li jdejjaq il - vini u l- arterji u li jista ’ jikkawża wkoll il- fibrożi, il- proliferazzjoni taċ- ċelluli, it- tkabbir tal- qalb, u jista ’ jerġa ’ jimmudella l- qalb u jippromwovi l- infjammazzjoni.
Last Update: 2012-04-10
Usage Frequency: 4
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