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this is an example from karen burg's lab, where they're using inkjet technologies to print breast cancer cells and study its progressions and treatments.
توی آزمایشگاه کارن برگ، آنها از فناوری پرینت جوهری استفاده می کنن تا سلولهای سرطان سینه رو پرینت کنن و پیشرفت و درمانشون رو مطالعه میکنن
Last Update: 2015-10-13
Usage Frequency: 1
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(and this proposition is generally true for all progressions and for all prime numbers; the proof of which i would send to you, if i were not afraid to be too long.
قضیه کوچک فرما که برای تمایز آن با قضیه آخر فرما به این نام موسوم است بیان میکند اگر یک عدد p اول و a عددی صحیح باشد که formula_1 دراین صورت formula_2.
Last Update: 2016-03-03
Usage Frequency: 1
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background: treatment with md1003 (high-dose biotin) showed promising results in progressive multiple sclerosis (ms) in a pilot open-label study. objective: to confirm the efficacy and safety of md1003 in progressive ms in a double-blind, placebo-controlled study. methods: patients (n = 154) with a baseline expanded disability status scale (edss) score of 4.5-7 and evidence of disease worsening within the previous 2 years were randomised to 12-month md1003 (100 mg biotin) or placebo thrice daily, followed by 12-month md1003 for all patients. the primary endpoint was the proportion of patients with disability reversal at month 9, confirmed at month 12, defined as an edss decrease of ⩾1 point (⩾0.5 for edss 6-7) or a ⩾20% decrease in timed 25-foot walk time compared with the best baseline among screening or randomisation visits. results: a total of 13 (12.6%) md1003-treated patients achieved the primary endpoint versus none of the placebo-treated patients (p = 0.005). md1003 treatment also reduced edss progression and improved clinical impression of change compared with placebo. efficacy was maintained over follow-up, and the safety profile of md1003 was similar to that of placebo. conclusion: md1003 achieves sustained reversal of ms-related disability in a subset of patients with progressive ms and is well tolerated.
چکیده زمینه: درمان با md1003 در یک مطالعه آزمایشی آزمایشی آزمایشی نتایج امیدوارکننده ای در مولتیپل اسکلروزیس پیشرونده (ms) نشان داد. هدف: برای تأیید کارایی و ایمنی md1003 در ms پیشرونده در یک مطالعه دوسوکور ، کنترل شده با دارونما. روش ها: بیماران (154 نفر) با مقیاس ابتدایی وضعیت ناتوانی (edss) نمره 4.5 7 و شواهدی از وخیم شدن بیماری در 2 سال گذشته به 12 ماه md1003 (100 میلی گرم بیوتین) یا روزانه سه بار دارونما تصادفی شدند ،
Last Update: 2020-11-04
Usage Frequency: 1
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