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prefrontal cortex
prefrontal kortex
Last Update: 2014-12-09
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lateral prefrontal cortex
prefrontal kortex
Last Update: 2014-12-09
Usage Frequency: 1
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preclinical research suggests guanfacine modulates signalling in the prefrontal cortex and basal ganglia through direct modification of synaptic noradrenalin transmission at the alpha 2- adrenergic receptors.
preklinisk forskning tyder på att guanfacin modulerar signalering i prefrontala cortex och basala ganglier genom direkt modifiering av synaptisk noradrenalintransmission vid alfa2-adrenerga receptorer.
they stimulate different cerebral structures, such as the prefrontal cortex, the amygdala and the hippocampus, which are part of a circuitry called the ‘reward system’.
de stimulerar olika hjärnstrukturer, till exempel prefrontala barken, amygdala och hippocampus, som ingår i det så kallade belöningssystemet.
it is thought that the active substance, guanfacine, might influence the way signals are transmitted between cells in areas of the brain called the prefrontal cortex and basal ganglia by attaching to certain receptors that are heavily concentrated in these areas.
man tror att den aktiva substansen, guanfacin, kan påverka sättet på vilket signaler överförs mellan celler i områden av hjärnan som kallas prefrontala cortex och basala ganglier, genom att substansen binder till vissa receptorer med kraftig koncentration i dessa områden.
note: meso-corticolimbic dopaminergic neurons from the ventral tegmental area and substantia nigra project to an important structure of the reward circuitry, the nucleus accumbens, and to the cortical areas primarily responsible for making decisions, such as whether to use drugs (e.g. the prefrontal cortex, and the cingulate gyrus).
dopaminerga utskott från mellanhjärnan till framhjärnan gyrus cinguli striatum prefrontala barken substantia nigra accumbenskärnan ventrala tegmentala arean
