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pioglitasoon teeb läbi ulatusliku metabolismi maksas, kus alifaatsed metüleenrühmad hüdroksüülitakse.
pioglitazone undergoes extensive hepatic metabolism by hydroxylation of aliphatic methylene groups.
Last Update: 2017-04-26
Usage Frequency: 3
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metabolism pioglitasoon teeb läbi ulatusliku metabolismi maksas, kus alifaatsed metüleenrühmad hüdroksüülitakse.
pioglitazone undergoes extensive hepatic metabolism by hydroxylation of aliphatic methylene groups.
Last Update: 2012-04-11
Usage Frequency: 2
Quality:
11 metabolism pioglitasoon teeb läbi ulatusliku metabolismi maksas, kus alifaatsed metüleenrühmad hüdroksüülitakse.
11 degree.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
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peamine metaboolne rada on deboroniseerumine kaheks deboroniseeritud metaboliidi vormiks, mis järgnevalt hüdroksüülitakse mitmeks metaboliidiks.
the major metabolic pathway is deboronation to form two deboronated metabolites that subsequently undergo hydroxylation to several metabolites.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
midasolaam hüdroksüülitakse tsütokroom p450 3a4 isoensüümi poolt ja peamiseks metaboliidiks uriinis ja plasmas on alfa- hüdroksümidasolaam.
midazolam is hydroxylated by the cytochrome p4503a4 isozyme and the major urinary and plasma metabolite is alpha-hydroxy-midazolam.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
inimorganismis enamik hüdrogeenitakse või hüdroksüülitakse ning peamised metaboliidid ion hüdroksü-6-deksametasoon ja dihüdro-20-deksametasoon.
the major part is hydrogenated or hydroxylated in humans, the major metabolites being hydroxy-6-dexamethasone and dihydro-20-dexamethasone.
Last Update: 2017-04-26
Usage Frequency: 1
Quality: