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ensüümkompleks, mis teadaolevalt reguleerib toremifeeni ainevahetust inimesel, on tsütokroom p450-st sõltuv maksa segafunktsiooniga oksüdaas.
enzyme complex, known to be responsible for the metabolism of toremifene in humans, is cytochrome p450-dependent hepatic mixed function oxidase.
Last Update: 2017-04-26
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fenobarbitooni ja β-naftoflavooni kasutamine ei ole vastuolus püsivate orgaaniliste saasteainete stockholmi konventsiooniga (50) ega määrusega (eÜ) nr 850/2004 (püsivate orgaaniliste saasteainete kohta) (66) ning on tõendatud, et see on segafunktsiooniga oksüdaaside indutseerimisel sama tõhus kui aroclor 1254 (46, 47, 48, 49).
the latter combination does not conflict with the stockholm convention on persistent organic pollutants (50) and regulation (ec) no 850/2004 on persistent organic pollutants (66) and has been shown to be as effective as aroclor 1254 for inducing mixed-function oxidases (46) (47) (48) (49).
Last Update: 2014-11-21
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