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metadoniannoksen muuttaminen ei ole tarpeen.
no dose adjustment of methadone is required.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
metadoniannoksen nostaminen voi tällöin olla tarpeen.
none of the subjects experienced withdrawal symptoms in this study; however, due to the pharmacokinetic changes, it should be expected that some patients who received this drug combination may experience withdrawal symptoms and require an upward adjustment of the methadone dose.
Last Update: 2011-10-23
Usage Frequency: 1
Quality:
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epclusa- tai metadoniannoksen muuttaminen ei ole tarpeen.
no dose adjustment of epclusa or methadone is required.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
metadoniannoksen suurentaminen voi olla tarpeen, kun lääkettä käytetään
increased methadone dose may be necessary when
Last Update: 2012-04-10
Usage Frequency: 2
Quality:
metadonin auc-arvo voi laskea käytettäessä sitä samanaikaisesti nelfinaviirin kanssa, jolloin metadoniannoksen nostaminen voi olla tarpeen.
methadone auc may be decreased when co-administered with nelfinavir; therefore upward adjustment of methadone dose may be required during concomitant use with nelfinavir.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
samanaikais esti annetun lääkeaineen cmax -arvoon glukuronidaation induktion takia metadoniannoksen suurentaminen voi olla tarpeen, jos samanaikaisesti käytetään ritonaviiria antiretroviraalisena aineena tai farmakokinetiikan tehostajana.
77% 108%the increases of plasma levels of buprenorphine and its active metabolite did not lead to clinically significant pharmacodynamic changes in a population of opioid tolerant patients.
Last Update: 2008-03-04
Usage Frequency: 1
Quality:
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metadonin auc- arvo voi laskea käytettäessä sitä samanaikaisesti viraceptin kanssa, jolloin metadoniannoksen nostaminen voi olla tarpeen (ks. kohta 4. 5).
methadone auc may be decreased when co-administered with viracept; therefore upward adjustment of methadone dose may be required during concomitant use with viracept (see section 4.5).
Last Update: 2012-04-10
Usage Frequency: 4
Quality:
metadoniannosta lisättiin keskimäärin 22% vieroitusoireiden poistamiseksi.
the methadone dose was increased by a mean of 22% to alleviate withdrawal symptoms.
Last Update: 2008-03-04
Usage Frequency: 13
Quality:
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