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toksisuustutkimuksiin perustuvat turvallisuusmarginaalit ovat pieniä eläinkoemalleissa havaitun annosta rajoittavan hypokalsemian vuoksi.
safety margins from the toxicology studies are small due to the dose-limiting hypocalcaemia observed in the animal models.
Last Update: 2017-04-26
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pegasysillä tehdyt prekliiniset toksisuustutkimukset ovat rajallisia johtuen interferonien spesifisyydestä eri lajeille.
the non-clinical toxicity studies conducted with pegasys were limited due to species specificity of interferons.
Last Update: 2012-04-10
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