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Αιιειεπηδξάζεηο κε άιια θαξκαθεπηηθά πξντόληα θαη άιιεο κνξθέο αιιειεπίδξαζεο
interaction with other medicinal products and other forms of interaction
Last Update: 2017-04-26
Usage Frequency: 5
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Πεξηνξηζκέλα δεδνκέλα απφ κηα κε ειεγρφκελε κειέηε ήηαλ ελδεηθηηθά κηαο αιιειεπίδξαζεο κεηαμχ ηεο docetaxel θαη ηεο carboplatin.
no statistically significant effect of prednisone on the pharmacokinetics of docetaxel was observed.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
Καηά ζπλέπεηα, πξέπεη λα δίδεηαη ηδηαίηεξε πξνζνρή θαηά ηε ζπγρνξήγεζε ηεο docetaxel κε ηα πξναλαθεξζέληα θαξκαθεπηηθά πξντφληα, δηφηη ππάξρεη πηζαλφηεηα ζεκαληηθήο αιιειεπίδξαζεο.
as a result, caution should be exercised when treating patients with these medicinal products as concomitant therapy since there is a potential for a significant interaction.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
Ιζρπξνί αλαζηνιείο ηεο p-gp: Μία κειέηε αιιειεπίδξαζεο εθάπαμ δφζεο ηνπ θαξκάθνπ ζε πγηείο εζεινληέο έρεη δείμεη φηη ε θπθινζπνξίλε (200 θαη 600 mg) απμάλεη ηελ cmax ηεο αιηζθηξέλεο 75 mg θαηά 2,5 θνξέο πεξίπνπ θαη ηελ auc θαηά 5 θνξέο πεξίπνπ.
p-gp potent inhibitors: a single dose drug interaction study in healthy subjects has shown that ciclosporin (200 and 600 mg) increases cmax of aliskiren 75 mg approximately 2.5-fold and auc approximately 5-fold.
Last Update: 2017-04-26
Usage Frequency: 1
Quality: