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galvenais klomipramīna biotransformācijas ceļš ir demetilācija par desmetilklomipramīnu.
the major route of biotransformation of clomipramine is demethylation to desmethylclomipramine.
Last Update: 2017-04-26
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pastāvīgās koncentrācijas periodā klomipramīna attiecība pret desmetilklomipramīnu plazmā ir apmēram 3:1.
at steady state, the ratio of plasma clomipramine to desmethylclomipramine concentrations is approximately 3:1.
Last Update: 2017-04-26
Usage Frequency: 3
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aktīvie komponenti in vivo ir klomipramīns un tā galvenais metabolīts, desmetilklomipramīns.
the active components in vivo are clomipramine and its major metabolite, desmethylclomipramine.
Last Update: 2017-04-26
Usage Frequency: 3
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