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klinikiniai duomenys parodė, kad buprenorfino 14-n dealkilinime dalyvauja cyp3a4.
clinical data confirm that cyp3a4 is responsible for the n- dealkylation of buprenorphine.
Last Update: 2017-04-26
Usage Frequency: 1
Quality:
metabolizmas aripiprazolas ekstensyviai metabolizuojamas kepenyse, daugiausia trimis biotransformacijos bdais: dehidrogenacijos, hidroksilinimo ir n-dealkilinimo.
metabolism:aripiprazole is extensively metabolised by the liver primarily by three biotransformation pathways: dehydrogenation, hydroxylation, and n-dealkylation.
Last Update: 2008-03-04
Usage Frequency: 9
Quality:
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