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Įrodyta, kad vykstant 5-fu anabolizmui blokuojama dezoksiuridilo rūgšties virtimo timidilo rūgštimi metilinimo reakcija, tokiu būdu veikiama dezoksiribonukleino rūgšties (dnr) sintezė.
there is evidence that the metabolism of 5-fu in the anabolic pathway blocks the methylation reaction of deoxyuridylic acid to thymidylic acid, thereby interfering with the synthesis of deoxyribonucleic acid (dna).
Last Update: 2017-04-26
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