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tirofiban. defibrotide.
tirofiban, defibrotide.
Last Update: 2017-04-26
Usage Frequency: 1
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is-sustanza attiva hija defibrotide.
the active substance is defibrotide.
Last Update: 2017-04-26
Usage Frequency: 1
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defitelio 80 mg/ml konċentrat sterili defibrotide
defitelio 80 mg/ml sterile concentrate defibrotide
Last Update: 2017-04-26
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ma nstabitx akkumulazzjoni ta’ defibrotide fuq 4 dożi.
accumulation of defibrotide over 4 doses was not found.
Last Update: 2017-04-26
Usage Frequency: 1
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kull kunjett ta' 2.5 ml fih 200 mg defibrotide.
each 2.5 ml vial contains 200 mg defibrotide.
Last Update: 2017-04-26
Usage Frequency: 1
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madankollu ebda farmakodinamika minn defibrotide ma ġiet identifikata in vivo.
however no pharmacodynamics effects from defibrotide have been identified in vivo.
Last Update: 2017-04-26
Usage Frequency: 1
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defitelio 80 mg/ml konċentrat għal soluzzjoni għal infużjoni defibrotide
defitelio 80 mg/ml concentrate for solution for infusion defibrotide
Last Update: 2017-04-26
Usage Frequency: 1
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defibrotide intwera wkoll li jkollu attività in vitro profibrinolitika dgħajfa.
defibrotide also has been shown to have a weak profibrinolytic activity in vitro.
Last Update: 2017-04-26
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ma hemm ebda studju dwar l-użu ta' defibrotide f'nisa tqal.
there are no studies using defibrotide in pregnant women.
Last Update: 2017-04-26
Usage Frequency: 1
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kull kunjett ta' 2.5 ml fih 200 mg defibrotide u kull ml soluzzjoni fiha 80 mg defibrotide.
each 2.5 ml vial contains 200 mg defibrotide and each ml solution contains 80 mg defibrotide.
Last Update: 2017-04-26
Usage Frequency: 1
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mhux magħruf jekk defibrotide jiġix eliminat mill-ħalib tas-sider tal-bniedem.
it is not known whether defibrotide is excreted in human milk.
Last Update: 2017-04-26
Usage Frequency: 1
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sensittività eċċessiva għal defibrotide jew għal kwalunkwe wieћed mill-eċċipjenti elenkati fis- sezzjoni 6.1
hypersensitivity to defibrotide or to any of the excipients listed in section 6.1
Last Update: 2017-04-26
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f’sottostudju ntwera li l-emodijalisi ma neħħietx defibrotide (ara sezzjoni 4.2).
in a sub-study it was shown that haemodialysis did not remove defibrotide (see section 4.2)
Last Update: 2017-04-26
Usage Frequency: 1
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għalhekk, l-użu ta' defibrotide ma' prodotti mediċinali antitrombotiċi/fibrinolitiċi mhuwiex rakkomandat.
therefore, the use of defibrotide with antithrombotic/fibrinolytic medicinal products is not recommended.
Last Update: 2017-04-26
Usage Frequency: 1
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defibrotide jaħdem billi jipproteġi ċ-ċelluli tal-vażi tad-demm u jimpedixxi jew ikisser l-emboli tad- demm.
defibrotide works by protecting the cells of the blood vessels and preventing or breaking down the blood clots.
Last Update: 2017-04-26
Usage Frequency: 1
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defibrotide intwera wkoll li jipproteġi ċ-ċelluli endoteljali minn apoptożi medjata bi fludarabine, filwaqt li ma għandux impatt fuq l-effett anti-lewkemiku tiegħu.
defibrotide has also been shown to protect endothelial cells from fludarabine-mediated apoptosis, while not impacting its anti-leukemic effect.
Last Update: 2017-04-26
Usage Frequency: 1
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barra minn hekk, defibrotide intwera li jżid il-funzjoni tal-attivatur tal-plasminoġen tat-tip tat-tessut (t- pa) u jnaqqas l-attività tal-inibitur-1 tal-attivatur tal-plasminogen (pai-1) u dan jirriżulta fi tnaqqis fl- attività prokoagulanti u f'żieda fil-potenzjal fibrinolitika taċ-ċelloli endoteljali.
also, in vitro, defibrotide has been shown to increase tissue-type plasminogen activator (t-pa) function and decrease plasminogen activator inhibitor-1 (pai-1) activity resulting in a decrease in procoagulant activity and an increase in the fibrinolytic potential of endothelial cells.
Last Update: 2017-04-26
Usage Frequency: 1
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