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barra dan zaleplon hu metabolizzat minn cyp3a4 sabiex jifforma desethylzaleplon li hu metaboliżat aktar b’aldehyde oxidase biex jifforma 5-oxo-desethylzaleplon.
additionally, zaleplon is metabolised by cyp3a4 to form desethylzaleplon which is further metabolised by aldehyde oxidase to form 5-oxo-desethylzaleplon.
Last Update: 2017-04-26
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sebgħa u ħamsin fil-mija (57%) tad-doża hi miġbura mill-awrina fil-forma ta’ 5-oxo-zaleplon u fil- metaboliti glukuronidi tiegħu, 9% oħra huma miġbura bħala 5-oxo-desethylzaleplon u fil-metaboliti gluċuronidi tiegħu.
fifty-seven percent (57%) of the dose is recovered in urine in the form of 5-oxo-zaleplon and its glucuronide metabolite, an additional 9% is recovered as 5-oxo-desethylzaleplon and its glucuronide metabolite.
Last Update: 2017-04-26
Usage Frequency: 3
Quality:
