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f’popolazzjonijiet fejn id-doża tista’ tiżdied sa’ 8 mg darba kuljum, iż-żieda fid-doża għandha ssir wara evalwazjoni tar-respons u t-tollerabilità.
in populations where the dose may be increased to 8 mg once daily, the dose increase should be preceded by an evaluation of the individual response and tolerability.