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Ġilda li tfarfar, ġilda li titqaxxar, skorċa u selħiet fid-demb bil-bidliet istopatoloġici korrelatati kienu nnutati b’dożi ta’ ≥ 20 mg/kg/jum (madwar 3 darbiet l-esponiment auc fil-bniedem bid-doża ta’ 100 mg).
flaking skin, peeling skin, scabs and tail sores with correlating histopathological changes were noted at doses ≥ 20 mg/kg/day (approximately 3 times human auc exposure at the 100 mg dose).
Last Update: 2017-04-26
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