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embryo-fetotoxicite a potrebe, aby ženy vo fertilnom veku 2 roky po implantácii používali účinnú antikoncepciu
embryo-foetotoxicity and the need for women with childbearing potential to use effective contraception for 2 years following implant
po liečbe gonadotropínmi existuje zvýšená možnosť viacpočetných tehotenstiev, aj keď sa do maternice prenesie len jedno embryo.
after treatment with gonadotrophin preparations, there is an increased chance of having multiple pregnancies, even when only one embryo is transferred into the uterus.
nilotinib nespôsoboval teratogenitu, ale vykazoval embryo- a fetotoxicitu pri dávkach, ktoré boli toxické aj pre samice.
nilotinib did not induce teratogenicity, but did show embryo- and foetotoxicity at doses that also showed maternal toxicity.
avšak štúdie u laboratórnych zvierat preukázali embryo-fetotoxické účinky, malformácie, oneskorenie pôrodu a zníženú životnosť mláďat.
however, studies with laboratory animals have shown embryo-foetotoxicity, malformations, delayed parturition and decreased pup survival.