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6 alfa-hidroxipaclitaxel es el componente principal que ha sido excretado en las heces.
6 alpha-hydroxypaclitaxel is the major component excreted in faeces.
Last Update: 2017-04-26
Usage Frequency: 4
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6 alfa-hidroxipaclitaxel, 3'-para-hidroxipaclitaxel y 6 alfa, 3'-para-dihidroxipaclitaxel.
6 alpha-hydroxypaclitaxel, 3'-para-hydroxypaclitaxel and 6 alpha, 3'-para-dihydroxypaclitaxel.
Last Update: 2012-04-10
Usage Frequency: 2
Quality:
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estudios in vitro han demostrado que cyp2c8 y 3a4 están implicados respectivamente, en la formación del 6 alfa-hidroxipaclitaxel y del 3'-para-dihidroxipaclitaxel.
in vitro studies have shown that cyp2c8 and 3a4 are involved in the formation of 6 alpha-hydroxypaclitaxel and 3'-para-dihydroxypaclitaxel, respectively.
Last Update: 2012-04-10
Usage Frequency: 2
Quality:
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de acuerdo con la literatura publicada, los estudios in vitro con microsomas y cortes tisulares hepáticos humanos muestran que paclitaxel se metaboliza principalmente a 6-hidroxipaclitaxel y a dos metabolitos minoritarios, 3'-p-hidroxipaclitaxel y 6-3'-p-dihidroxipaclitaxel.
based on the published literature, in vitro studies with human liver microsomes and tissue slices show that paclitaxel is metabolised primarily to 6-hydroxypaclitaxel; and to two minor metabolites, 3'-p-hydroxypaclitaxel and 6-3'-p-dihydroxypaclitaxel.
Last Update: 2008-03-04
Usage Frequency: 1
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Warning: This alignment may be wrong.
Please delete it you feel so.