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lamotrigin har en något hämmande effekt på dihydrofolsyrareduktas, varför det finns en risk för störning i folatmetabolismen under långvarig behandling (se avsnitt 4. 6).
lamotrigine has a slight inhibitory effect on dihydrofolic acid reductase, hence there is a possibility of interference with folate metabolism during long-term therapy (see section 4.6).
Last Update: 2012-04-11
Usage Frequency: 2
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lamotrigin har en svagt hämmande effekt på dihydrofolsyrareduktas och kan därför teoretiskt leda till ökad risk för embryo- fetal skada genom minskade folsyranivåer (se avsnitt 4. 4).
lamotrigine has a slight inhibitory effect on dihydrofolic acid reductase and could therefore theoretically lead to an increased risk of embryofoetal damage by reducing folic acid levels (see section 4.4).
Last Update: 2012-04-11
Usage Frequency: 2
Quality: