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när de väl aktiverats, fungerar dessa receptorer som ligandberoende transkriptionsfaktorer som reglerar expressionen av specifika gener.
once activated, these receptors function as ligand dependent transcription factors that regulate the expression of specific genes.
Last Update: 2017-04-26
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c5-expressionen i den humana vävnadspanel som testades i denna studie överensstämmer med publicerade rapporter om c5-expression, eftersom c5 har rapporterats i glatt muskulatur, tvärstrimmig muskulatur och proximalt tubulärt njurepitel.
c5 expression in the human tissue panel examined in this study is consistent with published reports of c5 expression, as c5 has been reported in smooth muscle, striated muscle, and renal proximal tubular epithelium.
Last Update: 2017-04-26
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baserat på in vitro-data är ibrutinib en svag inducerare av cyp2b6 och kan ha potentialen att påverka expressionen av andra enzymer och transportörer, som regleras via den konstitutiva androstanreceptorn (car), t.ex.
based on in vitro data, ibrutinib is a weak cyp2b6 inducer and may have the potential to affect the expression of other enzymes and transporters regulated via the constitutive androstane receptor (car), e.g.
Last Update: 2017-04-26
Usage Frequency: 1
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