Results for populationssekvensering translation from Swedish to English

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populationssekvensering

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Swedish

hos ingen av dessa försökspersoner kunde den sofosbuvir-associerade resistenssubstitutionen s282t påvisas med djupsekvensering eller populationssekvensering.

English

the sofosbuvir-associated resistance substitution s282t was not detected in any of these subjects by deep sequencing or population sequencing.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

Swedish

i fas 3-studier togs ns5b-sekvenser fram vid baseline för 1 292 försökspersoner med populationssekvensering, och s282t-substitutionen påvisades inte hos någon försöksperson med tillgänglig sekvens vid baseline.

English

baseline ns5b sequences were obtained for 1,292 subjects from phase 3 studies by population sequencing and the s282t substitution was not detected in any subject with available baseline sequence.

Last Update: 2017-04-26
Usage Frequency: 1
Quality:

Swedish

av 314 behandlingsnaiva och tidigare behandlade försökspersoner som inte uppnådde svr i fas 2/3-studier (p03523, p03659, p05216 och p05101) hos vilka boceprevirresistenta varianter hade uppstått under behandling, hade 73% (228/314) av försökspersonerna inte längre några påvisbara rav vid de lokus som associeras med boceprevirresistens, genom populationssekvensering inom 3 år efter avslutad behandling.

English

of 314 treatment-naïve and previously treated subjects who did not achieve svr from phase 2/3 studies (p03523, p03659, p05216, and p05101) in whom boceprevir-resistant variants had emerged during treatment, 73% (228/314) of subjects no longer had any ravs detected at the boceprevir-resistance associated loci by population sequencing within 3 years post-therapy.

Last Update: 2017-04-26
Usage Frequency: 1
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