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endokrin bezi
endocrine glands
Last Update: 2013-06-12
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hipertansiyona cushing sendromu, hipertroidizm, hiportroidizm, akromegali, conn sendromu ya da hiperaldosteronizm, hiperparatiroidizm ve feokromositoma gibi endokrin ile ilgili durumlar da sebep olabilir.
hypertension can also be caused by endocrine conditions, such as cushing's syndrome, hyperthyroidism, hypothyroidism, acromegaly, conn's syndrome or hyperaldosteronism, hyperparathyroidism and pheochromocytoma.
ve tabii ki, bu endokrin bozucular, göğüs kanseri salgınına, obezite salgınına, kızların ergenliğe girme yaşlarının 2.5 yıl erkene kaymasında ve benzeri şeylerde rol oynamaktadırlar.
and of course, these endocrine disruptors are things that are implicated in the breast cancer epidemic, the obesity epidemic, the two and a half year drop in the average age of onset of puberty in young girls and other related things.
== genler ==kromozom 11 üzerinde bulunan genlerden bazıları:* acat1: asetil koenzim a asetiltransferaz 1* atm: ataksia telangiectasia mutated* cpt1a: carnitine palmitoyltransferaz 1a* dhcr7: 7-dehidrokolestrol redüktaz* hbb: hemoglobin, beta* hmbs: hidroksimetilbilanesentetaz* hras: v-ha-ras harvey rat sarkoma viral onkogen homolog* kcnq1: potasyum voltaj-kapı kanalı* men1: multipl endokrin neoplazi i* mtmr2: myotubularin related protein 2* myo7a: myosin viia* pax6* pts: 6-piruvoiltetrahidropterin sentetaz* saa1: serum amyloid a1* sbf2: set binding factor 2* smpd1: sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase)* tecta: tectorin alpha (nonsyndromic deafness)* ush1c: usher sendromu 1c (otozomal çekinik, severe)== hastalıklar ==kromozom 11 üzerinde bulunan genlerle ilgili olan hastalıkların bazıları:* aniridia* akut intermittent porphyria* ataksia-telangiectasia* beta-ketothiolaz yetmezliği* beta talasemi* mesane kanseri* göğüs kanseri* karnitin palmitoyltransferaz i yetmezliği* charcot-marie-tooth hastalığı* charcot-marie-tooth hastalığı, tip 4* ailevi akdeniz ateşi* jacobsen sendromu* jervell ve lange-nielsen sendromu* meckel sendromu* methemoglobinemi, beta-globin tip* multiple endokrin neoplazi tip 1* niemann-pick hastalığı* sendromik olmayan sağırlık* sendromik olmayan sağırlık, otozomal baskın* sendromik olmayan sağırlık, otozomal çekinik* porphyria* romano-ward sendromu* orak hücreli anemi* smith-lemli-opitz sendromu* tetrahidrobiopterin yetmezliği* usher sendromu* usher sendromu tip i* wagr sendromu
==genes==the following are some of the genes located on chromosome 11:* acat1: acetyl-coenzyme a acetyltransferase 1 (acetoacetyl coenzyme a thiolase)* aplnr: apelin receptor (apj receptor)* apoa4: apolipoprotein a-iv* atm: ataxia telangiectasia mutated (includes complementation groups a, c and d)* bdnf:secretes bdnf, a member of the neurotrophin family of proteins* ccl9: chemokine (c-c motif) ligand 9* cd81* c11orf1* cpt1a: carnitine palmitoyltransferase 1a (liver)* dhcr7: 7-dehydrocholesterol reductase* hbb: hemoglobin, beta* hmbs: hydroxymethylbilane viia* ins: insulin gene* mmp7: matrix metalloproteinases (mmp family)* men1: multiple endocrine neoplasia type 1* pax6* pts: 6-pyruvoyltetrahydropterin synthase* saa1: serum amyloid a1* sbf2: set binding factor 2* smpd1: sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase)* tecta: tectorin alpha (nonsyndromic deafness)* th: tyrosine hydroxylase* ush1c: usher syndrome 1c (autosomal recessive, severe)* wt1: wilms tumor protein* rag1/rag2: recombination activating genes==diseases & disorders==the following diseases are some of those related to genes on chromosome 11:* autism (neurexin 1)* annidraedea* acute intermittent porphyria* albinism* ataxia-telangiectasia* beckwith-wiedemann syndrome* best's disease* beta-ketothiolase deficiency* beta thalassemia* bladder cancer* breast cancer* carnitine palmitoyltransferase i deficiency* charcot-marie-tooth disease* charcot-marie-tooth disease, type 4*cystic fibrosis*depression* denys-drash syndrome* familial mediterranean fever* hereditary angioedema* jacobsen syndrome* jervell and lange-nielsen syndrome* mantle cell lymphoma (t11;14)* meckel syndrome* methemoglobinemia, beta-globin type* mixed lineage leukemia* multiple endocrine neoplasia type 1* hereditary multiple exostoses* niemann-pick disease* nonsyndromic deafness* nonsyndromic deafness, autosomal dominant* nonsyndromic deafness, autosomal recessive* porphyria* potocki-shaffer syndrome* romano-ward syndrome* sickle cell anemia* smith-lemli-opitz syndrome* tetrahydrobiopterin deficiency* usher syndrome* usher syndrome type i* wagr syndrome* wilms' tumor==references==