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change the topic yaar
change the topic
Última actualización: 2018-04-14
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you change the dp
you change the dp
Última actualización: 2020-12-15
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i'll change the song
Última actualización: 2023-12-09
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practice can change the life
Última actualización: 2023-09-02
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advertisement script on the topic biscuit
advertisement script
Última actualización: 2018-06-06
Frecuencia de uso: 3
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change the gender of samrat in hindi
change the gender of samrat in hindi
Última actualización: 2020-09-09
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when you can't change the girl change the girl
when you can't change the girl change the girl
Última actualización: 2024-01-30
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what is the topic of the poem 'the road not taken
she should play cricket
Última actualización: 2020-09-18
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mohan is going to market change the passive voice
mohan is going to market change the passive voic
Última actualización: 2022-05-06
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education is the most powerful weapon which you can change the world
education is most powerful weapon which you can change the world
Última actualización: 2022-08-01
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one smile can't change the world, but your smile changes mine
one smile can change the world
Última actualización: 2022-03-14
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education is the most powerful weapon which you can.use to change the world
dreams is not what you see in sleep is the thing which doesn't let you sleep
Última actualización: 2022-04-23
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use your smile to change the world. don't let the world change your smile
Última actualización: 2020-08-29
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you can change your online password if you want to change the number of times you have to change your password
hardly come online in this number text me in this no 9619267827
Última actualización: 2022-10-06
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the world is what we think it is . if we can change our thoughts , we can change the world .
Última actualización: 2020-08-13
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i will play shuttle with my friends. rules of the game are cock should not touch the net. should not change the hand while playing
Última actualización: 2023-07-17
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this folder contains all the files which you see on your desktop. you can change the location of this folder if you want to, and the contents will move automatically to the new location as well.
this folder contains all the files which you see on your desktop. you can change the location of this folder if you want to, and the contents will move automatically to the new location as well.
Última actualización: 2023-06-29
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please i don't get what you're saying please can you change the site language to english and please bro reduce the price for ������
koi scam to nahi hai
Última actualización: 2023-07-01
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छवि बदलें हर (c): (qtdt- format) please do not change the quotes (') and translate only the content of the quotes.
change images every: (qtdt-format) please do not change the quotes (') and translate only the content of the quotes.
Última actualización: 2018-12-24
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duchenne muscular dystrophy, a severe type of muscle weakness that usually begins at an early age and worsens quickly, may soon have a new strategy of treatment through genetic regulation. there is no known cure for duchenne muscular dystrophy. treatments usually aim to control symptoms to improve quality of life. sandeep eswarappa, assistant professor indian institute of science (iisc), bengaluru one of the 21 recipients of this year’s swarnajayanti fellowship of the department of science and technology (dst), government of india proposes to supress the disease-causing premature stop codon or the genetic process that initiates these diseases. he is trying to bring about the suppression through translational readthrough, a gene regulatory principle found in humans, yeasts, bacteria and drosophila which takes place with the variation of the genetic code. prof. sandeep’s group has been developing strategies to induce translational readthrough across genetic diseases caused by non-sense mutations --a change in dna that causes a protein to terminate or end its translation earlier than expected. they were successful in achieving this in vitro in case of thalassemia and are working on other disease models. this research work has been published in the scientific journal ‘biochemistry’ recently. with the swarna jayanti fellowship, they will extend it to duchenne muscular dystrophy. if successful, this project may lead to novel therapeutics for the treatment of genetic diseases like thalassemia, duchenne muscular dystrophy, haemophilia. in case of any protein formation genetic information present in the genome is first transcribed into an mrna, which in turn is translated into a protein. protein synthesis or translation is executed by macromolecular machinery called ribosomes. ribosomes start this process at a specific location on an mrna called ‘start codon’ and terminate at a stop signal called ‘stop codon’. in case of diseases with nonsense mutations, such mutations result in premature stop signal in mrna often resulting in non-functional truncated protein. prof. sandeep eswarappa’s laboratory at iisc has shown that in certain mrnas, under certain conditions, translating ribosomes misread the stop signal and continue till they encounter another stop signal. in this translational readthrough process, a longer protein is synthesized with an extension. this extension might change the properties of the protein. the experiments carried out by his group have revealed that such long prote “the knowledge we have already gained from our experiment have opened an unexpected avenue to treat genetic diseases caused by non-sense mutations like duchenne muscular dystrophy, haemophilia and so on,” said prof. sandeep.
duchenne muscular dystrophy, a severe type of muscle weakness that usually begins at an early age and worsens quickly, may soon have a new strategy of treatment through genetic regulation. there is no known cure for duchenne muscular dystrophy. treatments usually aim to control symptoms to improve quality of life. sandeep eswarappa, assistant professor indian institute of science (iisc), bengaluru one of the 21 recipients of this year’s swarnajayanti fellowship of the department of science and technology (dst), government of india proposes to supress the disease-causing premature stop codon or the genetic process that initiates these diseases. he is trying to bring about the suppression through translational readthrough, a gene regulatory principle found in humans, yeasts, bacteria and drosophila which takes place with the variation of the genetic code. prof. sandeep’s group has been developing strategies to induce translational readthrough across genetic diseases caused by non-sense mutations --a change in dna that causes a protein to terminate or end its translation earlier than expected. they were successful in achieving this in vitro in case of thalassemia and are working on other disease models. this research work has been published in the scientific journal ‘biochemistry’ recently. with the swarna jayanti fellowship, they will extend it to duchenne muscular dystrophy. if successful, this project may lead to novel therapeutics for the treatment of genetic diseases like thalassemia, duchenne muscular dystrophy, haemophilia. in case of any protein formation genetic information present in the genome is first transcribed into an mrna, which in turn is translated into a protein. protein synthesis or translation is executed by macromolecular machinery called ribosomes. ribosomes start this process at a specific location on an mrna called ‘start codon’ and terminate at a stop signal called ‘stop codon’. in case of diseases with nonsense mutations, such mutations result in premature stop signal in mrna often resulting in non-functional truncated protein. prof. sandeep eswarappa’s laboratory at iisc has shown that in certain mrnas, under certain conditions, translating ribosomes misread the stop signal and continue till they encounter another stop signal. in this translational readthrough process, a longer protein is synthesized with an extension. this extension might change the properties of the protein. the experiments carried out by his group have revealed that such long proteins can have different localization, stability and function. “the knowledge we have already gained from our experiment have opened an unexpected avenue to treat genetic diseases caused by non-sense mutations like duchenne muscular dystrophy, haemophilia and so on,” said prof. sandeep.
Última actualización: 2021-03-15
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