Usted buscó: pegaspargase (Maltés - Inglés)

Is-sustanza attiva hi pegaspargase.
The active substance is pegaspargase.

Fih is-sustanza attiva pegaspargase.
It contains the active substance pegaspargase.

1 ml fih 750 U ta’ pegaspargase.
1 ml contains 750 U of pegaspargase.

Ma sarux studji bi pegaspargase dwar tossiċità riproduttiva.
No studies of reproductive toxicity were conducted with pegaspargase.

1 ml ta' soluzzjoni fih 750 unità ta' pegaspargase.
One ml of solution contains 750 units pegaspargase .

Oncaspar 750 U/ml soluzzjoni għall-injezzjoni/infużjoni pegaspargase
Oncaspar 750 U/ml solution for injection/infusion pegaspargase

1 ml ta' soluzzjoni fih 750 unità (U)** ta' pegaspargase*.
One ml of solution contains 750 units (U)** of pegaspargase*.

Kunjett wieħed ta' soluzzjoni ta' 5 ml fih 3750 unità ta' pegaspargase.
One vial of 5 ml solution contains 3750 units of pegaspargase.

Ma twettqux studji li jinvestigaw l-effett ta’ pegaspargase fuq il-fertilità.
No studies investigating the effect of pegaspargase on fertility have been performed.

Mhux magħruf jekk pegaspargase jiġix eliminat fil-ħalib tas-sider tal-bniedem.
It is not known whether pegaspargase is excreted into the breast milk.

Mhux magħruf jekk pegaspargase jiġix eliminat mill-ħalib tas-sider tal-bniedem.
It is not known whether pegaspargase is excreted into breast milk.

Pegaspargase ma kienx mutaġeniku fit-test Ames bl-użu ta' razez ta' Salmonella typhimurium.
Pegaspargase was not mutagenic in the Ames test using Salmonella typhimurium strains.

Antikorpi speċifiċi għal pegaspargase ġew imkejla; b’mod mhux komuni ġew assoċjati ma’ reazzjonijiet ta' sensittività eċċessiva.
Specific antibodies to pegaspargase have been measured; uncommonly they were associated to hypersensitivity reactions.

jekk inti allerġiku għal pegaspargase jew għal xi sustanza oħra ta’ din il-mediċina (elenkati fis- sezzjoni 6).
if you are allergic to pegaspargase or to any of the other ingredients of this medicine (listed in section 6).

Pegaspargase ġie ttollerat tajjeb kemm fil-firien kif ukoll fil-klieb meta mogħti ġol-vina f'doża waħda sa 500 U/kg.
Pegaspargase was well tolerated both in rats and dogs when administered intravenously in single dose up to 500 U/kg.

Billi pegaspargase hu proteina b’piż molekulari għoli, ma jiġix eliminat mill-kliewi, u l-ebda aġġustament fid-doża mhu meħtieġ f’pazjenti b’indeboliment tal-kliewi.
As pegaspargase is a protein with a high molecular weight, it is not excreted renally, and no dose adjustment is necessary in patients with renal impairment.

Studju fil-firien li dam 4 ġimgħat, b’dożaġġ ta’ 400 U/kg/jum ta’ pegaspargase ġol-peritonew wassal għal tnaqqis fil-konsum tal-ikel u l-piż tal-ġisem meta mqabbel mal-grupp ta' kontroll.
A 4-week study in rats with a dosage of pegaspargase of 400 U/kg/day intraperitoneal resulted in a fall in food intake and body weight compared to the control group.

Interazzjoni indiretta ma tistax tiġi eskluża bejn pegaspargase u kontraċettivi orali minħabba l- epatotossiċità ta' pegaspargase li tista' tfixkel it-tneħħija tal-kontraċettivi orali mill-fwied.
An indirect interaction cannot be ruled out between pegaspargase and oral contraceptives due to pegaspargase hepatotoxicity that may impair the hepatic clearance of oral contraceptives.

Dożi għoljin ħafna biss ta' pegaspargase mogħtija lill-ġrieden minn ġol-peritonew (i.p.) bħala doża waħda (25000 – 100000 U/kg ta' piż tal-ġisem) ikkawżaw il-mewt ta' 14% tal-ġrieden kollha kkurati.
Only very high doses of pegaspargase given to mice intraperitoneally as a single dose (25000 – 100000 U/kg body weight) caused the death of 14% of all treated mice.

Billi interazzjoni indiretta bejn il-komponenti tal-kontraċezzjoni orali u pegaspargase ma tistax tiġi eskluża, il-kontraċettivi orali mhumiex ikkunsidrati li huma siguri biżżejjed f'sitwazzjoni klinika bħal din.
Since an indirect interaction between components of the oral contraception and pegaspargase cannot be ruled out , oral contraceptives are not considered sufficiently safe in such clinical situation.