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eslicarbazepine acetate is rapidly and extensively biotransformed to its major active metabolite eslicarbazepine by hydrolytic first-pass metabolism.
eslikarbazepinacetat se brzo i opsežno biotransformira u njegov glavni aktivni metabolit eslikarbazepin putem hidrolitičkog metabolizma prvog prolaza.
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 1
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bimatoprost is biotransformed by any of multiple enzymes and pathways, and no effects on hepatic drug metabolising enzymes were observed in preclinical studies.
bimatoprost se biotransformira preko mnogih enzima i puteva razgradnje; u nekliničkim ispitivanjima nisu zabilježeni učinci na jetrene enzime koji metaboliziraju lijekove.
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 1
Qualité :
the primary pathway involves a cytosolic nadp+-linked enzyme, ghb dehydrogenase, that catalyses the conversion of sodium oxybate to succinic semialdehyde, which is then biotransformed to succinic acid by the enzyme succinic semialdehyde dehydrogenase.
primarni metabolički put uključuje citoplazmatski enzim povezan s nadp+, ghb- dehidrogenazu koja katalizira pretvaranje natrijeva oksibata u sukcinat-semialdehid koji se zatim pretvara dalje u sukcinatnu kiselinu enzimom sukcinat-semialdehid-dehidrogenaza.
Dernière mise à jour : 2017-04-26
Fréquence d'utilisation : 1
Qualité :
