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in such circumstances hypothalamic pituitary adrenocortical (hpa) axis function should be monitored regularly.
v takih okoliščinah je treba redno spremljati delovanje osi hipotalamus-hipofiza-nadledvična žleza (hpa).
pharmacotherapeutic group: pituitary and hypothalamic hormones and analogues, somatostatin and analogues, atc code: h01cb05
farmakoterapevtska skupina: hipofizni in hipotalamični hormoni in analogi, analogi somatostatina, oznaka atc: h01cb05
pharmacotherapeutic group: pituitary and hypothalamic hormones and analogues, somatropin and analogues, atc code: h01 ac 01
farmakoterapevtska skupina: hipofizni in hipotalamični hormoni ter sorodne učinkovine, somatropin in sorodne učinkovine, oznaka atc: h01ac01
pharmacotherapeutic group: pituitary and hypothalamic hormones and analogues, somatropin and somatropin agonists; atc code: h01ac01
farmakoterapevtska skupina: hormoni in analogi hipofize in hipotalamusa, somatropin in agonisti somatropina oznaka atc: h01ac01.
in particular, patients should be evaluated for hypothyroidism, adrenocortical deficiency, hyperprolactinemia and pituitary or hypothalamic tumours, and appropriate specific treatment given.
bolnice moramo zlasti pregledati glede hipotiroidizma, adrenokortikalne insuficience, hiperprolaktinemije in hipofiznih ali hipotalamičnih tumorjev in jih ustrezno specifično zdraviti.
patients with severe growth hormone deficiency in adulthood are defined as patients with known hypothalamic-pituitary pathology and at least one additional known deficiency of a pituitary hormone not being prolactin.
bolniki s hudim pomanjkanjem rastnega hormona v odrasli dobi so opredeljeni kot bolniki z znano patologijo osi hipotalamus–hipofiza in z vsaj enim dodatno znanim pomanjkanjem hipofiznega hormona, ki ni prolaktin.
in particular, patients should be evaluated for the following: • hypothyroidism • adrenocortical deficiency • hyperprolactinemia and pituitary or hypothalamic tumours
bolnike je treba še posebej pregledati na naslednje: • hipotiroidizem • adrenokortikalno insuficienco • hiperprolaktinemijo in tumorje hipofize ali hipotalamusa
the patient must have growth hormone deficiency as a result of hypothalamic or pituitary disease, and at least one other hormone deficiency diagnosed (except for prolactin).
bolnik mora imeti pomanjkanje rastnega hormona zaradi bolezni hipotalamusa ali hipofize ter diagnosticirano pomanjkanje vsaj še enega drugega hormona (razen prolaktina).
adult-onset: patients with ghd in adulthood are defined as patients with known hypothalamic-pituitary pathology and at least one additional known deficiency of a pituitary hormone excluding prolactin.
začetek v odrasli dobi: bolniki z ghd v odrasli dobi so opredeljeni kot bolniki z znano patologijo osi hipotalamus–hipofiza in z vsaj enim dodatno znanim pomanjkanjem hipofiznega hormona, ki ni prolaktin.
in patients with childhood-onset isolated growth hormone deficiency (no evidence of hypothalamic-pituitary disease or cranial irradiation), two dynamic tests should be recommended, except for those having low insulin-like growth factor-1 (igf-1) concentrations (< 2 standard deviation score (sds)), who may be considered for one test.
pri bolnikih z izoliranim pomanjkanjem rastnega hormona od otroštva dalje (brez dokazov bolezni osi hipotalamus–hipofiza ali obsevanja glave) je treba priporočiti dva dinamična testa, razen pri tistih z nizkimi koncentracijami insulinu podobnega rastnega dejavnika 1 (igf-1, insulin-like growth factor-1) (< 2 standardna odklona (sds, standard deviation score)), pri katerih zadošča en test.